Other genes[ edit ] A family with recessive osteogenesis imperfecta has been reported to have a mutation in the TMEM38B gene on chromosome 9. It is extremely likely that there are other genes associated with this disease that have yet to be reported. Pathophysiology[ edit ] People with OI are born with defective connective tissue, or without the ability to make it, usually because of a deficiency of Type-I collagen. The larger amino acid side-chains create steric hindrance that creates a bulge in the collagen complex, which in turn influences both the molecular nanomechanics and the interaction between molecules, which are both compromised.
This article has been cited by other articles in PMC. Majority of C1 fractures can be effectively treated conservatively by immobilization or traction unless there is an injury to the transverse ligament.
Conservative treatment usually involves a long period of immobilization in a halo-vest. Surgical intervention generally involves fusion, eliminating the motion of the upper cervical spine. We describe the treatment of unstable Jefferson fractures designed to avoid these problems of both conservative and invasive methods.
A retrospective review of 12 patients with unstable Jefferson fractures treated with transoral osteosynthesis of C1 between July and December was performed.
A steel plate and C1 lateral mass screw fixation were used to repair the unstable Jefferson fractures. Our study group included eight males and four females with an average age of 33 years range years. Patients were followed up for an average of 16 months after surgery.
Range of motion of the cervical spine was by and large physiologic: Total average lateral displacement of the lateral masses was 7. The total average difference of the atlanto-dens interval in flexion and extension after surgery was 1.
Transoral osteosynthesis of the anterior ring using C1 lateral mass screws is a viable option for treating unstable Jefferson fractures, which allows maintenance of rotation at the C1-C2 joint and restoration of congruency of the atlanto-occipital and atlantoaxial joints.
Conservative treatment of unstable Jefferson injuries includes immobilization and traction while surgical procedures typically involve posterior fusion of either C1-C2 or occiput-C2.
Eight males and four females with an average age of 33 years range years were evaluated. All patients underwent radiologic evaluation via plain cervical spine radiographs, computed tomography CT and magnetic resonance imaging MRI.
All patients complained of neck pain, stiffness and decreased range of motion without neurologic deficit. Five patients had anterior arch fractures with an associated posterior arch fracture semi-ring Jefferson fracture, Landells and Van Petegghem type II [ Figure 2A ].
One patient had an anterior arch fracture associated with aplasia of the posterior arch. Seven patients had an intact transverse ligament and five patients had avulsion of the insertion of the transverse ligament Dickman type II.
Raney-Crutchfield Tong was applied after admission to stabilize the fracture using weights between 2 and 3 kg.An apparatus for osteosynthesis comprises an oblong frame and at least four repositioning units.: Un appareil d' ostéosynthèse comprend une structure oblongue ainsi qu'au moins quatre unités de repositionnement.
bone screw, in particular for osteosynthesis: vis d'os, en particulier pour une ostéosynthèse: pin or screw-like securing device for osteosynthesis. The purpose of this study was to define patterns of injury and treatment for condylar and subcondylar fractures and evaluate short-term outcomes in the pediatric population.
A retrospective chart review was performed on pediatric patients with mandibular condylar fractures who presented between Achieving stable osteosynthesis in the mandible has been our mission starting with our initial work with Prof.
Champy in the 's. We have learned from this experience that the best solutions are both biomechanically intelligent and simple to use. These attributes define the benefits found in the ThreadLock TaperScrew (TS) and Rhombus. Conclusion The stability of the osteosynthesis by basket plate allows osseous consolidation of the fracture and per- mits immediate mobilization and early weight bearing.
May 22, · In load-bearing osteosynthesis, a rigid plate bears the forces of function at the fracture site. Indications are the management of atrophic edentulous fractures, comminuted fractures, and other complex mandibular fractures.
The Latin word flectere, meaning “to bend” or “to curve,” and its form flexus give us the roots flect and rutadeltambor.com from the Latin flectere have something to do with bending or curving.
To flex is to cause something, such as a muscle, to curve or bend. Something flexible can be bent without breaking. To deflect, or turn aside, is to bend the direction of something.